Avaliação da relação entre eventos traumáticos infantis e comportamentos autolesivos em adolescentes / Evaluation of the relationship between childhood traumatic events and self-injurious behavior in adolescents / Evaluación de la relación entre eventos traumáticos infantiles y comportamiento autolesivo en adolescentes

Esta pesquisa teve como objetivo verificar a relação entre eventos traumáticos (ET) na infância e a ocorrência de comportamentos autolesivos em adolescentes. Os instrumentos utilizados foram o Questionário sobre Traumas na Infância (QUESI) e o Inventário de Autolesão Deliberada - reduzido (IAD-r). Participaram 494 estudantes do ensino médio de ambos os sexos e idade entre 15 e 18 anos (M = 16,4). Destes, 58,5% afirmaram ter sofrido abuso emocional de forma recorrente e 19,0% e 59,5% assumiram já ter sofrido abuso sexual e físico, respectivamente. Quanto à prática de autolesão, 65,0% revelaram já ter se engajado em comportamentos autolesivos. De acordo com a análise de Regressão Logística Binomial, todos os tipos de ET exibiram associação significativa com a prática de comportamentos autolesivos. A análise de moderação a respeito da interação entre a ocorrência de ET infantis e a prática de autolesão revelou ausência de moderação pelo sexo e pela idade. Porém, quanto ao abuso físico, o efeito de moderação da idade apresentou significância estatística limítrofe e indicou que os adolescentes mais novos, de 15 e 16 anos, que sofreram este tipo de abuso na infância, foram mais susceptíveis à prática autolesiva. Portanto, as altas taxas de ET e de autolesão encontradas nesta pesquisa revelam a gravidade do problema. Espera-se que esta investigação possa contribuir para a elaboração de intervenções para prevenção e controle dos fatores de risco que acometem a população infanto-juvenil.(AU)

This research aimed to verify the relationship between traumatic events (TE) in childhood and the occurrence of self-injurious behavior in adolescents. The instruments used were the Childhood Trauma Questionnaire (QUESI) and the Deliberate Self-Injury Inventory - reduced (IAD-r). The sample was composed of 494 high school students of both genders and aged between 15 and 18 years old (M = 16.4). Of those, 58.5% declared to have suffered recurring emotional abuse and 19.0% declared to have suffered sexual abuse and 59.5% physical abuse. Regarding the practice of self-harm, 65.0% reported having already engaged in self-injurious behaviors. According to the Binomial Logistic Regression analysis, all types of TE were associated with the practice of self-injurious behaviors. The moderation analysis between the occurrence of childhood TE and self-injury showed no moderation by sex or age. However, regarding physical abuse, the moderating effect of age showed borderline statistical significance and indicated that younger adolescents, 15 and 16 years old, who suffered this type of abuse in childhood, were more susceptible to self-injurious behavior. Therefore, the high rates of TE and self-injury found in this research reveal the seriousness of the problem. It is hoped for this investigation to contribute to the development of interventions to prevent and control risk factors that affect children and adolescents.(AU)

Esta investigación tuvo como objetivo verificar la relación entre eventos traumáticos (ET) en la infancia y la ocurrencia de conductas autolesivas en adolescentes. Los instrumentos utilizados fueron el Cuestionario de Trauma Infantil (QUESI) y el Inventario de Autolesiones Deliberadas -reducido (IAD-r). Participaron 494 estudiantes de la secundaria, de ambos sexos y con edades entre 15 y 18 años (M = 16,4). De estos, el 58,5% afirmaron haber sufrido maltrato emocional de forma recurrente, el 19,0% dijeron haber sufrido maltrato sexual y el 59,5%, maltrato físico. En cuanto a la práctica de la autolesión, el 65,0% informaron haber realizado conductas autolesivas. El análisis de Regresión Logística Binomial mostró que todos los tipos de ET tuvieron una asociación significativa con la práctica de conductas autolesivas. El análisis de la moderación respecto a la interacción entre la ocurrencia de ET infantil y la práctica de la autolesión reveló una ausencia de moderación por sexo o edad. En cuanto al maltrato físico, el efecto moderador de la edad mostró una significación estadística marginal e indicó que los adolescentes más jóvenes, de 15 y 16 años, que sufrieron este tipo de maltrato en la infancia, son más susceptibles a la práctica de autolesiones. Por lo tanto, las altas tasas de ET y autolesiones encontradas en esta investigación revelan la gravedad del problema. Se espera que esta investigación contribuya con el desarrollo de intervenciones para la prevención y control de los factores de riesgo que afectan a niños y adolescentes.(AU)

Estrategias de afrontamiento en pacientes con cáncer. Un estudio de centro único / Coping strategies in cancer patients. A single-center study

ntroducción: El diagnóstico de cáncer genera una inestabilidad emocionaly en muchos casos esto im-posibilita unafrontamiento adecuado.El afrontamiento es el esfuerzocognitivoy conductualconstan-temente cambiantes que se desarrollan para manejar las demandas específicas como el diangóstico oncológico. El objetivo de la presente investigación fue identificar las estrategias de afrontamiento en un grupo de pacientes con cáncer, en un Hospital de referencia nacional. Metodología: Este estudio transversal, se realizó en el Hospital Eugenio Espejo de Quito, Ecuador, período enero a junio del 2018, con una muestra no probabilística, de pacientes con neoplasias, se registraron variables demográficas, clínicas, y el test de afrontamiento de 40 preguntas CSI "El inventario de estrategias de afrontamiento (CSI). Se utiliza estadística descriptiva invariada y bivariado. Resultados: Se analizan 47 casos, 74% mujeres, de edad promedio 55 años. De instrucción secundaria completa en el 38%de los casos. Las Estrategias de Afrontamiento que se presentaron en el 70% de los pacientes fueron: Reestructuración Cognitiva (REC) y Evitación de problemas (EVP), en el 15% se presentó "Resolución de problemas" (REP). Las Estrategias de Afrontamiento en hombres fueron REP con el 57%, mientras que la Expresión Emocional (EEM) se presentó en mujeres en el 86%.En los prime-ros 6 meses el 77% usa la EEM; de 7 a 12 meses el 19% a la estrategia de Autocrítica (AUC); de 1 a 2 años con un 17% estrategia de Pensamiento Desiderativo (PSD); de 3 o más años con un 14% corresponde a Resolución de Problemas (REP).Conclusión: Las estrategias de afrontamientos utilizan en gran proporción en los primeros 6 meses del diagnóstico del cáncer, luego de lo cual las estrategias disminuyen por debajo del 20%

Introduction:The cancer diagnosis generates emotional instability, which precludes adequate coping in many cases. Coping is the constantly changing cognitive and behavioral effort that develops to handle specific demands such as cancer diagnosis. This research aimed to identify coping strategies in a group of cancer patients in a national reference hospital.Methodology: This cross-sectional study was carried out at the Eugenio Espejo Hospital in Quito, Ecua-dor, from January to June 2018, with a non-probabilistic sample of patients with neoplasms,demo-graphic and clinical variables were recorded, and the coping test of 40 CSI questions "The Coping Strat-egies Inventory (CSI). Univariate and bivariate descriptive statistics are used.Results: 47 cases were analyzed, 74% women, with an average age of 55. Complete secondary education in 38% of cases. The Coping Strategies that appeared in 70% of the patients were: Cognitive Restructur-ing (REC) and Problem Avoidance (EVP); in 15%, "Problem Resolution" (REP) was presented. Coping Strategies in men were REP with 57%, while Emotional Expression (EEM) was presented in women with 86%. In the first six months, 77% use the EEM; from 7 to 12 months, 19% to the Self-criticism strategy (AUC); from 1 to 2 years with 17% Wishful Thinking Strategy (PSD); of 3 or more years with 14% corre-sponds to Resolution of Problems (REP).Conclusion: Coping strategies are significantly used in the first six months after the cancer diagnosis, after which the strategies decrease below 20%

Transtorno distímico: uma ilustração clínica pela perspectiva da Terapia Cognitivo-Comportamental e Terapia Cognitiva Processual / Dysthimic disorder: clinical illustration from the perspective of Cognitive- Behavioral Therapy and Processual Cognitive Therapy

O presente trabalho tem como objetivo ilustrar como a articulação entre a Terapia Cognitivo Comportamental e a Terapia Cognitiva Processual possibilita resultado satisfatório em casos de Trantorno distímico. Os estudos acerca do transtorno distímico ainda são limitados. No entanto, o caso clínico corrobora com a literatura, que aponta a importância dos psicofarmacos no tratamento dos transtornos de humor, bem como a importância da psicoterapia, inclusive em casos mais brandos, como os de distimia. A Terapia Congitivo Comportamental clássica não foi suficente para a melhora significativa da paciente, sendo necessário o acréscimo de técnicas da Tereapia Cognitiva Processual. Essa articulação das abordagens nas intervenções psicoterápicas proporcionou mudanças significativas no padrão de pensamento, sentimento e comportamento da paciente.(AU)

This paper aims to illustrate how the articulation between Cognitive-Behavioral Therapy and Cognitive Processual Therapy enables satisfactory results in cases of dysthymic disorder. Studies on dysthymic disorder are still limited. However, the clinical case corroborates the literature, which points out the importance of psychopharmaceuticals in the treatment of mood disorders, as well as the importance of psychotherapy even in milder cases such as dysthymia. The classic Cognitive-Behavioral Therapy was not enough for the patients significant improvement, and the addition of Cognitive Processual Therapy techniques was necessary. This articulation of approaches in psychotherapeutic interventions provided significant changes in the patients pattern of thinking, feeling, and behaving.(AU)

El presente trabajo pretende ilustrar cómo la articulación entre la Terapia Cognitivo Conducutal y la Terapia Cognitiva Procesal permite obtener resultados satisfactorios en casos de trastorno distímico. Los estudios sobre el trastorno distímico son todavía limitados. Sin embargo, el caso clínico corrobora la literatura, que señala la importancia de los psicofármacos en el tratamiento de los trastornos del estado de ánimo, así como la importancia de la psicoterapia, incluso en los casos más leves, como la distimia. La clásica Terapia CognitivoConductual no fue suficiente para la mejora significativa del paciente, siendo necesaria la adición de técnicas de la Terapia Cognitiva Procesal. Esta articulación de enfoques en las intervenciones psicoterapéuticas condujo a cambios significativos en el patrón de pensamiento, sentimiento y comportamiento del paciente.(AU)

Ansiedad, depresión, bienestar subjetivo y salud mental general en reclusos / Anxiety, depression, subjective well-being and general mental health in inmates

Introducción: El estudio de variables psicológicas asociadas al encarcelamiento, reviste esencial importancia en la actualidad. Se ha reportado la vivencia de estados psicológicos patológicos en individuos dentro de las prisiones. Objetivo: Describir los estados de ansiedad, depresión, bienestar psicológico y el estado de salud mental general de los reclusos en regímenes de prisión provisional y prisión severa. Métodos: Se empleó un enfoque cuantitativo con un tipo de estudio transversal y descriptivo, mediante el uso de cuestionarios. La población fueron los internos de los regímenes de prisión provisional y severos (grupo de prisión provisional y grupo de severos). Los instrumentos empleados fueron: Escala de Bienestar Subjetivo; Cuestionario de Salud Mental General de Goldberg; Escala de Zung y Conde; e Inventario de Situaciones y Respuestas de Ansiedad. Los datos se analizaron mediante el paquete estadístico SPSS para Windows: versión 22.0. Se utilizó la estadística descriptiva y la Prueba T para muestras independientes. El estudio se llevó a cabo entre enero y mayo de 2019. Resultados: Se observó alta percepción del deterioro de la salud mental general. El bienestar subjetivo mostró valores similares en ambos grupos, con mínimas diferencias entre los altos y bajos niveles de bienestar. La mayoría de los participantes mostró niveles de ansiedad moderada. La vivencia de depresión también fue elevada; se observó distimia moderada y grave. Todos los participantes del régimen de prisión provisional, presentaron alguna variante de depresión. Conclusiones: Se encontraron altos niveles de ansiedad, depresión y un alto deterioro de la salud mental general. Se reportaron bajos índices de percepción de bienestar subjetivo(AU)

Introduction: The study of psychological variables associated with incarceration is of essential importance today. The experience of pathological psychological states has been reported in individuals within prisons. Objective: To describe the states of anxiety, depression, psychological well-being and the general state of mental health of inmates in provisional prison and severe prison regimes. Methods: A quantitative approach was used with a type of cross-sectional and descriptive study through surveys. The population was the inmates of the provisional and severe prison regimes. The instruments used were: Subjective Well-being Scale; Goldberg General Mental Health Questionnaire; Zung and Conde scale; and Inventory of Anxiety Situations and Responses. The data were analyzed using the statistical package SPSS for Windows: version 22.0. Descriptive statistics and the T-test were used for independent samples. The study was carried out from January to May 2019. Results: A high perception of the deterioration of general mental health was observed. Subjective well-being showed similar values in both sample groups, with minimal differences between high and low levels of well-being. Most of the participants showed moderate anxiety levels. The experience of depression was also high; moderate and severe dysthymia were observed. All the participants of the provisional prison regime presented some variant of depression. Conclusions: High levels of anxiety, depression and a high deterioration of general mental health were found. Low rates of subjective well-being perception were reported(AU)

Evaluación neuropsicológica de los procesos cognitivos básicos en pacientes distímicos con intento de suicidio / Neuropsychological assessment of basic cognitive processes in dysthymic patients attempted suicide

La distimia incluye síntomas crónicos que interfieren en el funcionamiento y bienestar de la persona, pudiendo traer consecuencias fatales como el intento de suicidio, así como alteraciones neuropsicológicas en los procesos afectivos y cognitivos que afectan el comportamiento. En el municipio de Guisa, Provincia Granma, existe un alto número de pacientes distímicos que son infradiagnosticados, por lo que las conductas suicidas se tornan más frecuentes. Por este motivo se realizó la investigación que se muestra bajo el título “Evaluación neuropsicológica de los procesos cognitivos básicos en pacientes distímicos con intento de suicidio”, con el objetivo de caracterizar el estado neuropsicológico de dichos procesos. Se aplicaron métodos del nivel teórico: análisis-síntesis y el inductivo-deductivo, así como las siguientes técnicas: entrevista inicial, anamnesis, observación, Inventario de Beck, test Gestáltico Bisomotor, Tarea de denominación de objetos, Tarea go/no go, Series gráficas y motoras alternantes, Test de memoria acortado y el Test de la figura compleja de Rey. A través de los cuales se obtuvo que el estado neuropsicológico de los procesos cognitivos básicos en estos pacientes está alterado, manifestando déficits en la percepción, atención y memoria, sustentados en posibles hallazgos biológicos en determinadas áreas cerebrales. Este trabajo investigativo es de vital importancia, permitirá diseñar intervenciones terapéuticas acertadas para el tratamiento, convirtiéndose de esta manera la exploración neuropsicológica en un elemento clave para el diagnóstico e intervención en los pacientes.

Dysthymia includes chronic symptoms that interfere with the functioning and well-being of the person and can bring fatal consequences such as suicide attempt, and neuropsychological alterations in affective and cognitive processes that affect behavior. In the municipality of Guisa, Granma Province there is a high number of dysthymic patients are underdiagnosed, so suicidal behavior become more frequent. For this reason, research shown under the title "Neuropsychological assessment of basic cognitive processes in dysthymic patients attempted suicide" in order to characterize the neuropsychological status of basic cognitive processes in these patients was performed. Analysis-synthesis and inductive-deductive and the following techniques: initial interview, anamnesis, observation, Inventory Beck, test Gestalt Bisomotor,Task object naming, Task go / no go, graphics series theoretical methods were applied and alternating motor, shortened memory test and test the complex figure of Rey. Through which was obtained that the neuropsychological status of basic cognitive processes in these patients is altered, showing deficits in perception, attention and memory, sustained in possible biological findings in certain brain areas. This research work is vital, it will allow designing successful therapeutic interventions for treatment, thus becoming the neuropsychological a key for diagnosis and intervention in these patient’s element.

Frequency of Depression and Suicidality in Patients with Neurological Disorders: Epilepsy, Parkinson's Disease, and Ischemic Stroke

BACKGROUND: Depression and suicide are common in neurological disorders. However, their reported frequencies have varied widely due to heterogeneities in methodology and assessment timing. We evaluated the frequencies of current depression and suicidality in patients with epilepsy, Parkinson's disease (PD), and ischemic stroke (IS). METHODS: We enrolled patients who visited a tertiary care hospital in Seoul between January and December 2013. All of the patients completed the Beck Depression Inventory (BDI) and the Hospital Anxiety and Depression Scale-Depression subscale (HADS-D). Any patient with depressive symptoms (defined as a total HADS-D or BDI score of ≥9 or ≥17, respectively) was reassessed with a structured psychiatric interview based on the Mini International Neuropsychiatric Interview Plus 5.0.0 (MINI). RESULTS: In total, 305 patients were recruited, comprising epilepsy (n=92, 30.2%), PD (n=99, 32.4%), and IS (n=114, 37.4%). Depressive symptoms were exhibited by 52 epilepsy patients (56.5%), 56 PD patients (56.6%), and 54 IS patients (47.4%), and these were further evaluated with the aid of the MINI. Seven epilepsy patients were diagnosed as major depressive disorder (MDD), five as dysthymic disorder (DD), and nine as depressive disorder not otherwise specified (DDNOS). Twelve PD patients were diagnosed as MDD, 7 as DD, and 10 as DDNOS. Ten stroke patients were diagnosed as MDD, 7 as DD, and 11 as DDNOS. Most patients with depressive symptoms (91.4%) exhibited suicidality. CONCLUSIONS: Patients with epilepsy, PD, and IS frequently exhibit depression and suicidality. Neurologists should always be concerned about comorbid psychiatric problems when they see patients with neurological disorders.

Screening for depressive disorders in outpatients with mild to moderate psoriasis: A study from North India.

Background: Psoriasis and depressive disorders commonly occur together. Depressive disorders have an impact on the quality of life and the outcome of psoriasis. Aims: The aim of this study was to test the feasibility of using a modifi cation of the Hindi translation of the Patient Health Questionnaire-9 (PHQ-9) as a verbal, clinician administered, short screening questionnaire for detecting depressive disorders. Materials and Methods: One hundred and four out-patients with psoriasis were recruited in the study. In the fi rst stage of the study, socio-demographic data, Psoriasis Area Severity Index (PASI) score, and Dermatological Quality of Life (DLQI) score were recorded. The modifi ed questionnaire was administered by the dermatologist. In the second stage, psychiatric diagnoses were confi rmed using the Mini International Neuropsychiatric Interview. Results: The prevalence of depressive disorders was 39.4%. Receiver operating curve (ROC) analysis showed that the questionnaire had a good discriminant ability in detecting depressive disorders (area under curve: 0.81, SE = 0.04, 95% confi dence interval = 0.72–0.89). Limitations: The sample size is small and more studies are needed with the screening questions in different languages to validate the fi ndings of the study. Conclusion: The questionnaire can be a useful screening instrument for detecting depressive disorders in patients with psoriasis.

Factores asociados a ideación suicida en universitarios / Factors Associated with Suicidal Ideation in College Students

Estudio no experimental de tipo transeccional descriptivo cuyo objetivo fue identificar los factores asociados a ideación suicida en una muestra de 258 universitarios con edades comprendidas entre los 18 y los 24 años, pertenecientes a una universidad ubicada en el departamento de Boyacá; a partir del inventario de ideación suicida positiva y negativa (PANSI), la Escala de autoevaluación para la depresión de Zung (SDS), la Escala de impulsividad de Barratt (BIS), el Cuestionario de dependencia emocional (CDE), la Escala de eventos vitales estresantes (EEVA) y una ficha sociodemográfica. El análisis de resultados indican que el 31 % de la población participante presentó ideación suicida, hallándose a partir de las pruebas U de Mann-Whitney y Kruskal Wallis, que el estado civil unión libre, los eventos vitales estresantes, la dependencia emocional, la impulsividad y la depresión son factores asociados a ideación en universitarios.

Transactional descriptive non-experimental study aimed to identify factors associated with suicidal ideation in a sample of 258 college students aged between 18 and 24 years old, belonging to a university located in the Boyacá state; through the Positive and Negative Suicide Ideation Inventory (PANSI), the Zung Self-Rating Depression Scale (SDS), the Barratt Impulsiveness Scale (BIS), Emotional Dependency Questionnaire (CDE), Stressful Life Events Scale (EEVA) and a socio-demographic questionnaire. The analysis results indicate 31 % of the participant population had suicidal ideation, being from the U Mann-Whitney and Kruskal Wallis, the common law marital status, stressful life events, emotional dependency, impulsivity and depression are factors associated with suicidal ideation in college.

Psychiatric comorbidity in diabetes type 1: a cross-sectional observational study / Comorbidade psiquiátrica no diabetes tipo 1: um estudo transversal observacional

Objective This study aims to investigate the prevalence of psychiatric disorders, i.e., the presence of signs and symptoms of anxiety and depression in type 1 diabetic patients, as well as to investigate the prevalence of psychiatric disorders in insulin dependent patients. Methods A cross-sectional observational study of 110 diabetic outpatients (mean = 58.3, SD = 14.5; 50 male and 60 female) was conducted in a public health clinic with patients diagnosed with diabetes mellitus who were under the medical supervision of an endocrinologist. The patients were evaluated through the Mini International Neuropsychiatric Interview and the Hospital Anxiety and Depression Scale(HADS). Results With respect to anxiety symptoms, we found a prevalence of 60% (n = 66) among patients, while in depression symptoms we found a prevalence of 53.6% (n = 59) concerning the 110 patients evaluated. More specifically, we found 28.2% (n = 31) of patients without depression or anxiety, 13.6% (n = 15) of patients with depression, 16.4% (n = 18) of patients with anxiety and 41.8% (n = 46) of patients with depression combined with anxiety. The most remarkable data were generalized anxiety disorder (22.7%), dysthymia (18.2%), panic disorder (8.2%) and social phobia (5.5%). Conclusion The need for accurate assessments about the presence of symptoms related to psychopathology in patients with type 1 diabetes is evident. .

Objetivo Elementos relacionados à saúde mental do paciente diabético tipo 1 são encontrados em várias pesquisas. O objetivo desse estudo é avaliar sinais e sintomas depressivos nesse grupo de pacientes, como também investigar as principais prevalências psiquiátricas que os acometem. Métodos Pesquisa realizada em 110 pacientes diabéticos atendidos em ambulatórios (média = 58.3, D = 14.5; 50 masculinos e 60 femininos) conduzida em Postos de Saúde Pública nos momentos de consulta médica com endocrinologista. A avaliação transcorreu com as escalas Mini International Neuropsychiatric Interview and Hospital Anxiety and Depression Scale (HADS). Resultados Os sintomas de ansiedade tiveram prevalência de 60% (n = 66), enquanto para depressão encontramos resultados de 53.6% (n = 59), considerando que 110 pacientes foram avaliados. Mais especificamente, nós encontramos 28,2 (n. 31) pacientes sem depressão ou ansiedade, 13,6 (n. 15) pacientes com depressão, 16,4 pacientes (n. 18) com ansiedade e 41,8 (n. 46) pacientes com depressão combinada com ansiedade. Outros transtornos comórbidos tiveram prevalência de ansiedade generalizada (22,7%), distimia (18,2%), pânico (8,2%) e fobia social (5,5%). Conclusão Sintomas ansiosos e depressivos são comuns em pacientes diabéticos do tipo 1, porém há prevalência de psicopatologias diversas nesse grupo de pacientes, levando em conta novas necessidades de pesquisas futuras para validar protocolos de tratamentos mais adequados para diabéticos do tipo 1. .

Comorbid Depressive Disorders in ADHD: The Role of ADHD Severity, Subtypes and Familial Psychiatric Disorders

OBJECTIVE: To evaluate the presence of Major Depressive Disorder (MDD) and Dysthymic Disorder (DD) in a sample of Italian children with Attention Deficit Hyperactivity Disorder (ADHD) and to explore specific features of comorbid depressive disorders in ADHD. METHODS: Three hundred and sixty-six consecutive, drug-naive Caucasian Italian outpatients with ADHD were recruited and comorbid disorders were evaluated using DSM-IV-TR criteria. To evaluate ADHD severity, parents of all children filled out the ADHD Rating Scale. Thirty-seven children with comorbid MDD or DD were compared with 118 children with comorbid conduct disorder and 122 without comorbidity for age, sex, IQ level, family psychiatric history, and ADHD subtypes and severity. RESULTS: 42 of the ADHD children displayed comorbid depressive disorders: 16 exhibited MDD, 21 DD, and 5 both MDD and DD. The frequency of hyperactive-impulsive subtypes was significantly lower in ADHD children with depressive disorders, than in those without any comorbidity. ADHD children with depressive disorders showed a higher number of familial psychiatric disorders and higher score in the Inattentive scale of the ADHD Rating Scale, than children without any comorbidity. No differences were found for age, sex and IQ level between the three groups. CONCLUSION: Consistent with previous studies in other countries, depressive disorders affect a significant proportion of ADHD children in Italy. Patient assessment and subsequent treatment should take into consideration the possible presence of this comorbidity, which could specifically increase the severity of ADHD attention problems.

Sintomatología depresiva y función reflexiva en la psicoterapia psicodinámica con pacientes distímicas: comparación de tres casos / Depressive symptoms and reflective function of dysthymic patients in a psychodynamic psychotherapy: a comparison of three single cases

El estudio examina empíricamente la relación entre el estado de ánimo depresivo y la mentalización en el curso de la terapia. Las preguntas de investigación fueron: ¿Pueden observarse cambios en el estado de ánimo depresivo y / o en la mentalización en el curso de la terapia? ¿Puede observarse una relación entre el síntoma depresivo cardinal y la mentalización? Método: La muestra se compuso de tres casos únicos homogéneos en cuanto a sexo, edad, diagnóstico y resultado del tratamiento. La terapia incluyó como mínimo 50 sesiones. Los instrumentos utilizados fueron Profile of Mood States (POMS) para medir la Depresión y Reflective Functioning Scale para medir la Función Reflexiva (Reflective Function, RF). Para el análisis estadístico se utilizó la correlación de rangos de Spearman. Resultados: En los tres casos se observó una tendencia descendente para la variable Depresión. La RF disminuyó en un caso, y en dos casos no se modificó. Sólo en un caso se halló una correlación (negativa) entre Depresión y RF. Conclusiones: En estudios futuros deberá investigarse una muestra más amplia y homogénea. Se recomienda la utilización de un diseño de investigación y de métodos estadísticos más complejos, así como la inclusión de diversas variables de proceso.

La distimia en el contexto clínico / Dysthymia in the Clinical Context

La distimia se define como un trastorno afectivo crónico que persiste por lo menos dos años en adultos y un a ño en adolescentes y niños. Según el DSM IV-TR, se clasifica en dos subtipos: la distimia de inicio temprano, antes de los 21 años, y la de inicio tardío después de los 21 años. Generalmente antes de los 21 años se puede observar trastornos de conducta, déficit de atención e hiperactividad y algunos síntomas vegetativos. Es importante distinguir tempranamente la distimia de otros tipos de depresión, a fin de brindar un tratamiento oportuno que atenúe el impacto continuo de síntomas caracterizados por pobre conciencia del estado de ánimo, pensamiento negativo, baja autoestima y anergia, lo que deteriora progresivamente la calidad de vida. La etiología es compleja y multifactorial, dados los variados mecanismos biológicos, psicológicos y sociales involucrados. Varias hipótesis tratan de explicar la etiología de la distimia; destacan la hipótesis genética que incluye además factores ambientales y la hipótesis aminérgica, que apunta a una deficiencia de serotonina, noradrenalina y dopamina en el sistema nervioso central. Desde nuestro punto de vista, no se puede concebir la distimia como un simple trastorno depresivo leve; es una entidad diferente caracterizada por un trastorno depresivo crónico que puede persistir toda la vida, con importantes repercusiones en la calidad de vida, tanto del sujeto que la padece como de sus familiares.

Dysthymia is defined as a chronic mood disorder that persists for at least two years in adults, and one year in adolescents and children. According to DSM IV-TR, Dysthymia is classified into two subtypes: early-onset, when it begins before 21 years-old, and late onset Dysthymia, when it starts after this age. Before age 21, symptoms of conduct disorder, attention deficit disorder and hyperactivity with a few vegetative symptoms are usually present. It is important to distinguish it from other types of depression, as earlier as possible. This would allow providing these patients with the appropriate treatment to attenuate the impact of symptoms, such as poor awareness of self-mood, negative thinking, low self-esteem, and low energy for social and family activities, which progressively deteriorate their life quality. The etiology of Dysthymia is complex and multifactorial, given the various biological, psychological and social factors involved. Several hypotheses attempt to explain the etiology of Dysthymia, highlighting the genetic hypothesis, which also includes environmental factors, and an aminergic hypothesis suggesting a deficiency in serotonin, norepinephrine and dopamine in the central nervous system. From our point of view, dysthymia cannot be conceived as a simple mild depressive disorder. It is a distinct entity, characterized by a chronic depressive disorder which could persist throughout life, with important repercussions on the life quality of both patients and families.

Effectiveness of cognitive-behavioral therapy in decreasing suicidal ideation and hopelessness of the adolescents with previous suicidal attempts

To evaluate the effectiveness of a Cognitive-Behavioral therapy [CBT] for suicide prevention in decreasing suicidal ideation and hopelessness in a sample of depressed 12 to 18 year-old adolescents who had at least one previous suicidal attempt. In a clinical trial, 30 depressed adolescents who attempted suicide in the recent 3 months were selected using simple sampling method and divided randomly into intervention and wait-list control groups. Both groups received psychiatric interventions as routine. The intervention group received a 12 session [once a week] of CBT program according to the package developed by Stanley et al, including psychoeducational interventions and individual and family skills training modules. All of the patients were evaluated by Scale for Suicidal Ideation, Beck's hopelessness Inventory, and Beck's Depression Inventory before the intervention and after 12 weeks. There were significant differences between the two groups regarding the scores of the above mentioned scales after 12 weeks. Fifty-four to 77 percent decreases in the mean scores of the used scales were observed in the invention group. There were no significant changes in the scores of the control wait-list group. The differences between pre- and post-intervention scores in the intervention group were significant. CBT is an effective method in reducing suicidal ideation and hopelessness in the depressed adolescents with previous suicidal attempts

Prevalence of Depressive Disorder among the Elderly Attending Community Health Center in a Small City / 신경정신의학

OBJECTIVES: This study was conducted in order to collect data regarding depressive disorder of elderly people at a community health center. METHODS: A total of 109 elderly people participated in this study. Trained examiners evaluated the general characteristics and symptoms of the subjects. Then the doctors conducted interviews with the elderly subjects in person and diagnosed depressive disorder according to the standard of Diagnostic and Statistical Manual of Mental Disorders-IV-TR. RESULTS: The prevalence of depressive disorder was 19.3%, major depressive disorder 10.1%, dysthymic disorder 1.8%, and others 7.3%. According to results of logistic regression analysis, in terms of demographic variables, the odds ratio of elementary school dropout compared with elementary school graduates was 3.60, after adjusting for age and sex. Thus, we found that elementary school dropout was associated with an increased risk of prevalence of depression. CONCLUSION: This is the first study of prevalence of depressive disorder in a primary health care center in Korea. Results of this study confirm that the prevalence of depressive disorder is two times higher among adults in the Chungju community. In addition, the level of education was also highly related. Examiners detected a possible relationship between sex and residence. The results will be helpful in conduct of future studies at the health care center.

Korean Medication Algorithm for Depressive Disorder 2012 (III): The Subtypes of Depression / 대한정신약물학회지

OBJECTIVE: Recently, the pharmacotherapy including antidepressants in treating depression is widely used. However, as a result of newer agents that are continuously introduced, pharmacological treatment strategy is also changing. To catch up this trend, Korean Medication Algorithm Project for Depressive Disorder was developed in 2002 and revised in 2006. Since the last revision, the third revision reflected the new research result and the latest trends in the areas of pharmacological treatment. METHODS: One hundred and twenty three psychiatrists who have vast clinical experiences in depressive disorder are primarily selected then survey was sent to them via mail, 67 surveys were retried. This survey is constructed with 44 questionnaires in which contained from overall treatment strategies to treatment strategies under the specific circumstances. Each treatment strategy or treatment option is evaluated with the overall score of nine and the following 95% confidence interval result treatment option were divided into three phases of recommendation; primary, secondary, tertiary. RESULTS: For dysthymic disorder, antidepressant monotherapy including selective serotonin reuptake inhibitor (SSRI) [(es)citalopram, fluoxetine, sertraline, paroxetine], serotonin-norepinephrine reuptake inhibitor (SNRI) (venlafaxine, duloxetine, milacipran), and mirtazapine, was recommended as the first line medications. For melancholic type, SSRI, SNRI, and mirtazapine were recommended as the first line medications. For atypical type and seasonal pattern, bupropion as well as SSRI, SNRI, and mirtazapine, were recommended as the first line medications. CONCLUSION: The preferences of antidepressants in experts were different according to the subtype of depression. These results suggest that clinicians have to consider the subtype of depression in the treatment of depressive disorders.

Impacto da cronicidade do transtorno distímico na qualidade de vida / Impact of dysthymic disorder cronicity on quality of life

A distimia diferencia-se da depressão por sua cronicidade e menor severidade sintomatológica. A cronicidade acarreta sérios prejuízos na rotina dos pacientes, atividades laborais, relacionamentos sociais e qualidade de vida. O objetivo deste estudo foi explorar o impacto do transtorno distímico na qualidade de vida dos pacientes. Utilizou-se uma entrevista semiestruturada com 24 pacientes distímicos, sendo os dados analisados pelo software Alceste. Neste artigo, discutiu-se a classe sobre o Tratamento da Distimia e Qualidade de Vida. Observou-se um ciclo de tristeza que interfere no dia a dia, acarretando insatisfação e frustração, retroalimentando a baixa autoestima, que induziria à continuidade dos sintomas, passando a fazer parte da experiência cotidiana do indivíduo e aparecendo, por fim, como um modo de ser. A partir desses dados, sugere-se que o transtorno possa ser interpretado por novos parâmetros, baseados na compreensão dessa sucessão de processos, que deveria ser o foco da intervenção com tais pacientes.

Dysthymia is differentiated from depression by its chronicity and less symptomatic severity. Chronicity causes severe harm in the routine of patients, work activities, social relationships and quality of life. The aim of this study was to explore the impact of dysthymic disorder on patients' quality of life. A semi-structured interview was held with 24 dysthymic patients and the data were analyzed by the Alceste software. In this article, the lexical class in the Treatment of dysthymia and Quality of Life was discussed. There was a cycle: sadness that interferes with day-to-day life, causing frustration and dissatisfaction, with feedback to low self-esteem, which would lead to continuity of symptoms, becoming part of the individual's everyday experience, and finally, appearing to be a way of being. From these data, it is suggested that the disorder may be interpreted by new parameters, based on the understanding of this succession of processes, which should be the focus of intervention in these patients.

The Effects of Triallelic Serotonin Transporter Gene Polymorphism and Stressful Life Event on Depression in Patients with Alcohol Dependence

OBJECTIVES: The purpose of this study is to investigate the relationship between the triallelic serotonin transporter gene and stressful life events to determine their effect on depression with alcohol dependence. METHODS: Ninety-five hospitalized patients with alcohol dependence (73 male, 22 female) were enrolled in this study. Thirty-two (33.7%) of the total patients were diagnosed with major depressive disorder and dysthymic disorder by Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders-IV. The characteristics of stress were evaluated using the stressful life events scale, and depressive symptoms were assessed using the depression scale (Beck Depression Inventory, BDI). Alcoholism with depression (n = 32) and alcoholism without depression (n = 63) were genotyped for the triallelic serotonin transporter gene (LA : higher expressing allele, LG/S : lower expressing allele). RESULTS: There was no significant difference in the allele frequency between the depression group and the non-depression group (chi2 = 0.345, p = 0.619). LG/S alleles had more comorbid depression in the higher score of stressful life events scale [Mental-Haenszel (MH)-chi2 = 4.477, p = 0.034]. But there was no significant difference in the comorbidity according to the scores from the stressful life event scale in the LA alleles (MH-chi2 = 0.741, p = 0.399). In the results, alcohol-dependent individuals with LG/S alleles had more comorbid depression than those with LA alleles when they had experienced severe stressful life events (MH-odds ratio = 2.699, p = 0.028). CONCLUSIONS: These results suggest that there is no direct relationship between triallelic serotonin transporter gene and depression in the alcohol dependent patients. But alcohol dependent individuals with the lower expressing alleles of the serotonin transporter gene were more susceptible to depression than those with the higher expressing alleles in response to stressful life events.

"How much can I take?": predictors of perceived burden for relatives of people with chronic illness

<p><b>INTRODUCTION</b>Chronic illnesses are common and have detrimental effects not only on the affected individuals but also on their families. These negative consequences on the physical and psychological health of caregivers constitute the burden of care. We investigate the predictors of perceived burden of care among relatives of people with any chronic physical or mental illness using secondary data from a nationwide survey in Singapore.</p><p><b>MATERIALS AND METHODS</b>A cross-sectional household survey was conducted among adult residents of age 18 years and above and data were analysed to explore the predictors of high perceived burden of care. Two thousand four hundred and fifty-eight respondents having at least 1 close relative with any chronic physical and/or mental illness were included.</p><p><b>RESULTS</b>Majority of the respondents had at least 1 close family member with physical illness (88.3%)--the most common illnesses reported were memory problems (86.9%), physical disability (74.8%), heart problems (70.1%) and cancer (62.2%). About 30.9% (n = 723) perceived high burden resulting from their relatives' health condition. Logistic analysis showed that women were more likely (OR 1.58, P = 0.0026) and Malays were less likely (OR 0.68, P = 0.0044) to perceive burden. Those who were able to open up to their family or friends (OR 1.65, P = 0.0162) and those who had dysthymia had higher odds (OR 4.91, respectively, P =0.0364) of perceiving burden.</p><p><b>CONCLUSION</b>Our results suggest that regardless of the nature of the chronic illnesses, gender or ethnicity, the capacity to open up to family or friends and the mental health status of caregivers can predict their perceived burden. The results provide valuable preliminary information for planning social policies and interventions for improving the well-being of caregivers.</p>

Depression, Inflammation, and Oxidative Stress in Peritoneal Dialysis Patients: Is There a Relationship? / 대한신장학회지

PURPOSE: This study aimed to investigate the features and severity of depressive symptoms in peritoneal dialysis patients, and the relationship of depressive symptoms with levels of inflammation and oxidative stress (OS). METHODS: The diagnosis of depression was made using DSM-IV-TR and the depressive symptoms were evaluated using the Hamilton Rating Scale for Depression (HRSD) via a semi-structured interview. Levels of thiobarbituric acid-reactive substances (TBARs) were determined as markers of lipid peroxidation. Superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px) activities were measured as antioxidants. RESULTS: 19 (28.8%) patients were diagnosed with depression (Major Depressive Disorder was 18.2%, Dysthymic disorder was 10.6%). OS markers were not different between patients with and without depression. Compared to non-depressed patients, depressed patients showed significantly higher depressed mood, feelings of guilt, suicidal ideation, sleep disturbances, psychomotor retardation, agitation, psychic and somatic anxiety, lower levels of work and activities, gastrointestinal and general somatic symptoms, and hypochondriasis. There was a significant positive correlation between HRSD scores and peritonitis (gamma=0.297, p=0.016), levels of high sensitivity C-reactive protein (hsCRP) (gamma=0.406, p=0.001) and ferritin (gamma=0.276, p=0.025), while there was a significant negative correlation between scores of HRSD and levels of albumin (gamma=-0.313, p=0.010). CONCLUSION: Major depressive disorder and dysthymic disorder were not related to inflammation and oxidative stress in peritoneal dialysis patients; however, depressive symptom severity was correlated with markers of inflammation and malnutrition. These results suggest that inflammation could have influence on depressive symptoms in peritoneal dialysis patients.

The Influence of Life Stress on the Severity of Depression and Somatic Symptoms in Depressive Women / 신경정신의학

OBJECTIVES: Stressful life events play the important role in depression. Somatic symptoms have also been closely linked to life stress. This study aimed to investigate the influence of life stress during four different life stages (childhood, adolescent, from 19 years to last year, the year prior to interview) on the severity of depression and somatic symptoms in depressive women. METHODS: Seventy women who had been diagnosed with major depressive disorder or dysthymic disorder according to the DSM-IV TR, and whose ages varied from 21 to 72 years (average age : 41 years), completed the Mooney Problem checklist, the Beck Depression Inventory (BDI), and Wittenborn`s somatic symptom scale. RESULTS: Life stressors which significantly influenced the severity of depression were difficulties with parents in the initial life stage, difficulties with other people in the third and fourth stages, and difficulties with social relationships in the fourth stage Further, somatic symptoms were influenced by health problem in the second period, difficulties with partners were prominent in the third stage, and difficulties with other people were noted in the fourth stage. The severity of depression showed a significantly positive correlation both with autonomic nervous system (p<0.001) and menopausal symptoms (p<0.001). After controlling for age, the severity of depression showed a significant positive correlation with stressors in the first stage (p<0.05), third stage (p<0.05), and fourth stage (p<0.01). Somatic symptom scores exhibited a significantly positive correlation with stressors in the second (p<0.05) and fourth stages (p<0.05). CONCLUSION: Current results suggested that the severity of depression and somatic symptoms were influenced by difficulties with other people in the fourth stage. The results of this study suggests that depression and somatic symptoms can be abbreviated by regulating excess stress.